My Bibliography

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Shiekhattar R, Bibbs EG, Schowen RL, Adams RN. Rapid chemical sampling of endogenous species from brain slice preparations. Neurosci Lett. 1990 Mar 26;111(1-2):189-94. doi: 10.1016/0304-3940(90)90366-h. PubMed PMID: 1970858.

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Aston-Jones G, Shipley MT, Chouvet G, Ennis M, van Bockstaele E, Pieribone V, Shiekhattar R, Akaoka H, Drolet G, Astier B. Afferent regulation of locus coeruleus neurons: anatomy, physiology and pharmacology. Prog Brain Res. 1991;88:47-75. doi: 10.1016/s0079-6123(08)63799-1. Review. PubMed PMID: 1687622.

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Shiekhattar R, Aston-Jones G, Chiang C. Local infusion of calcium-free solutions in vivo activates locus coeruleus neurons. Brain Res Bull. 1991 Jul;27(1):5-12. doi: 10.1016/0361-9230(91)90273-m. PubMed PMID: 1933435.

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Shiekhattar R, Aston-Jones G. Local application of bicuculline potentiates NMDA-receptor-mediated sensory responses of brain noradrenergic neurons. Synapse. 1992 Jan;10(1):54-61. doi: 10.1002/syn.890100108. PubMed PMID: 1346944.

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Shiekhattar R, Aston-Jones G. NMDA-receptor-mediated sensory responses of brain noradrenergic neurons are suppressed by in vivo concentrations of extracellular magnesium. Synapse. 1992 Feb;10(2):103-9. doi: 10.1002/syn.890100204. PubMed PMID: 1533954.

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Shiekhattar R, Ghasemzadeh MB, Adams RN. Intracerebral infusion of DOPAC decreases striatal dopamine. Brain Res Bull. 1992 Dec;29(6):891-6. doi: 10.1016/0361-9230(92)90161-p. PubMed PMID: 1473020.

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Ennis M, Aston-Jones G, Shiekhattar R. Activation of locus coeruleus neurons by nucleus paragigantocellularis or noxious sensory stimulation is mediated by intracoerulear excitatory amino acid neurotransmission. Brain Res. 1992 Dec 11;598(1-2):185-95. doi: 10.1016/0006-8993(92)90182-9. PubMed PMID: 1336704.

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Shiekhattar R, Aston-Jones G. Sensory responsiveness of brain noradrenergic neurons is modulated by endogenous brain serotonin. Brain Res. 1993 Sep 24;623(1):72-6. doi: 10.1016/0006-8993(93)90011-b. PubMed PMID: 8221096.

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Shiekhattar R, Aston-Jones G. Modulation of opiate responses in brain noradrenergic neurons by the cyclic AMP cascade: changes with chronic morphine. Neuroscience. 1993 Dec;57(4):879-85. doi: 10.1016/0306-4522(93)90032-b. PubMed PMID: 8309548.

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Shiekhattar R, Aston-Jones G. Activation of adenylate cyclase attenuates the hyperpolarization following single action potentials in brain noradrenergic neurons independently of protein kinase A. Neuroscience. 1994 Sep;62(2):523-9. doi: 10.1016/0306-4522(94)90385-9. PubMed PMID: 7830895.

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Shiekhattar R, Mermelstein F, Fisher RP, Drapkin R, Dynlacht B, Wessling HC, Morgan DO, Reinberg D. Cdk-activating kinase complex is a component of human transcription factor TFIIH. Nature. 1995 Mar 16;374(6519):283-7. doi: 10.1038/374283a0. PubMed PMID: 7533895.

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Maldonado E, Shiekhattar R, Sheldon M, Cho H, Drapkin R, Rickert P, Lees E, Anderson CW, Linn S, Reinberg D. A human RNA polymerase II complex associated with SRB and DNA-repair proteins. Nature. 1996 May 2;381(6577):86-9. doi: 10.1038/381086a0. PubMed PMID: 8609996.

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Reinberg D, Orphanides G, Ebright R, Akoulitchev S, Carcamo J, Cho H, Cortes P, Drapkin R, Flores O, Ha I, Inostroza JA, Kim S, Kim TK, Kumar P, Lagrange T, LeRoy G, Lu H, Ma DM, Maldonado E, Merino A, Mermelstein F, Olave I, Sheldon M, Shiekhattar R, Zawel L. The RNA polymerase II general transcription factors: past, present, and future. Cold Spring Harb Symp Quant Biol. 1998;63:83-103. doi: 10.1101/sqb.1998.63.83. Review. PubMed PMID: 10384273.

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Lambert PF, Kashanchi F, Radonovich MF, Shiekhattar R, Brady JN. Phosphorylation of p53 serine 15 increases interaction with CBP. J Biol Chem. 1998 Dec 4;273(49):33048-53. doi: 10.1074/jbc.273.49.33048. PubMed PMID: 9830059.

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Zerby D, Chen CJ, Poon E, Lee D, Shiekhattar R, Lieberman PM. The amino-terminal C/H1 domain of CREB binding protein mediates zta transcriptional activation of latent Epstein-Barr virus. Mol Cell Biol. 1999 Mar;19(3):1617-26. doi: 10.1128/MCB.19.3.1617. PubMed PMID: 10022850; PubMed Central PMCID: PMC83956.

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Bochar DA, Pan ZQ, Knights R, Fisher RP, Shilatifard A, Shiekhattar R. Inhibition of transcription by the trimeric cyclin-dependent kinase 7 complex. J Biol Chem. 1999 May 7;274(19):13162-6. doi: 10.1074/jbc.274.19.13162. PubMed PMID: 10224071.

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Schmidt AE, Miller T, Schmidt SL, Shiekhattar R, Shilatifard A. Cloning and characterization of the EAP30 subunit of the ELL complex that confers derepression of transcription by RNA polymerase II. J Biol Chem. 1999 Jul 30;274(31):21981-5. doi: 10.1074/jbc.274.31.21981. PubMed PMID: 10419521.

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Bochar DA, Savard J, Wang W, Lafleur DW, Moore P, Côté J, Shiekhattar R. A family of chromatin remodeling factors related to Williams syndrome transcription factor. Proc Natl Acad Sci U S A. 2000 Feb 1;97(3):1038-43. doi: 10.1073/pnas.97.3.1038. PubMed PMID: 10655480; PubMed Central PMCID: PMC15513.

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Schang LM, Hwang GJ, Dynlacht BD, Speicher DW, Bantly A, Schaffer PA, Shilatifard A, Ge H, Shiekhattar R. Human PC4 is a substrate-specific inhibitor of RNA polymerase II phosphorylation. J Biol Chem. 2000 Mar 3;275(9):6071-4. doi: 10.1074/jbc.275.9.6071. PubMed PMID: 10692395.

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Guenther MG, Lane WS, Fischle W, Verdin E, Lazar MA, Shiekhattar R. A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness. Genes Dev. 2000 May 1;14(9):1048-57. PubMed PMID: 10809664; PubMed Central PMCID: PMC316569.

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Bochar DA, Wang L, Beniya H, Kinev A, Xue Y, Lane WS, Wang W, Kashanchi F, Shiekhattar R. BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer. Cell. 2000 Jul 21;102(2):257-65. doi: 10.1016/s0092-8674(00)00030-1. PubMed PMID: 10943845.

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Marmorstein LY, Kinev AV, Chan GK, Bochar DA, Beniya H, Epstein JA, Yen TJ, Shiekhattar R. A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression. Cell. 2001 Jan 26;104(2):247-57. doi: 10.1016/s0092-8674(01)00209-4. PubMed PMID: 11207365.

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Kamura T, Burian D, Khalili H, Schmidt SL, Sato S, Liu WJ, Conrad MN, Conaway RC, Conaway JW, Shilatifard A. Cloning and characterization of ELL-associated proteins EAP45 and EAP20. a role for yeast EAP-like proteins in regulation of gene expression by glucose. J Biol Chem. 2001 May 11;276(19):16528-33. doi: 10.1074/jbc.M010142200. Epub 2001 Feb 5. PubMed PMID: 11278625.

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Lo WS, Duggan L, Emre NC, Belotserkovskya R, Lane WS, Shiekhattar R, Berger SL. Snf1--a histone kinase that works in concert with the histone acetyltransferase Gcn5 to regulate transcription. Science. 2001 Aug 10;293(5532):1142-6. doi: 10.1126/science.1062322. PubMed PMID: 11498592.

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Hakimi MA, Bochar DA, Chenoweth J, Lane WS, Mandel G, Shiekhattar R. A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes. Proc Natl Acad Sci U S A. 2002 May 28;99(11):7420-5. doi: 10.1073/pnas.112008599. PubMed PMID: 12032298; PubMed Central PMCID: PMC124246.

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Hakimi MA, Bochar DA, Schmiesing JA, Dong Y, Barak OG, Speicher DW, Yokomori K, Shiekhattar R. A chromatin remodelling complex that loads cohesin onto human chromosomes. Nature. 2002 Aug 29;418(6901):994-8. doi: 10.1038/nature01024. PubMed PMID: 12198550.

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Hakimi MA, Speicher DW, Shiekhattar R. The motor protein kinesin-1 links neurofibromin and merlin in a common cellular pathway of neurofibromatosis. J Biol Chem. 2002 Oct 4;277(40):36909-12. doi: 10.1074/jbc.C200434200. Epub 2002 Aug 20. PubMed PMID: 12191989.

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Hakimi MA, Dong Y, Lane WS, Speicher DW, Shiekhattar R. A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes. J Biol Chem. 2003 Feb 28;278(9):7234-9. doi: 10.1074/jbc.M208992200. Epub 2002 Dec 18. PubMed PMID: 12493763.

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Cho DS, Yang W, Lee JT, Shiekhattar R, Murray JM, Nishikura K. Requirement of dimerization for RNA editing activity of adenosine deaminases acting on RNA. J Biol Chem. 2003 May 9;278(19):17093-102. doi: 10.1074/jbc.M213127200. Epub 2003 Mar 4. PubMed PMID: 12618436.

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Dong Y, Hakimi MA, Chen X, Kumaraswamy E, Cooch NS, Godwin AK, Shiekhattar R. Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair. Mol Cell. 2003 Nov;12(5):1087-99. doi: 10.1016/s1097-2765(03)00424-6. PubMed PMID: 14636569.

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Barak O, Lazzaro MA, Lane WS, Speicher DW, Picketts DJ, Shiekhattar R. Isolation of human NURF: a regulator of Engrailed gene expression. EMBO J. 2003 Nov 17;22(22):6089-100. doi: 10.1093/emboj/cdg582. PubMed PMID: 14609955; PubMed Central PMCID: PMC275440.

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Barak OG, Shiekhattar R. Preparation and assays for mammalian ISWI complexes. Methods Enzymol. 2004;377:389-401. doi: 10.1016/S0076-6879(03)77025-6. PubMed PMID: 14979040.

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Tang J, Wu S, Liu H, Stratt R, Barak OG, Shiekhattar R, Picketts DJ, Yang X. A novel transcription regulatory complex containing death domain-associated protein and the ATR-X syndrome protein. J Biol Chem. 2004 May 7;279(19):20369-77. doi: 10.1074/jbc.M401321200. Epub 2004 Feb 27. PubMed PMID: 14990586.

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Barak O, Lazzaro MA, Cooch NS, Picketts DJ, Shiekhattar R. A tissue-specific, naturally occurring human SNF2L variant inactivates chromatin remodeling. J Biol Chem. 2004 Oct 22;279(43):45130-8. doi: 10.1074/jbc.M406212200. Epub 2004 Aug 13. PubMed PMID: 15310751.

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Gregory RI, Yan KP, Amuthan G, Chendrimada T, Doratotaj B, Cooch N, Shiekhattar R. The Microprocessor complex mediates the genesis of microRNAs. Nature. 2004 Nov 11;432(7014):235-40. doi: 10.1038/nature03120. Epub 2004 Nov 7. PubMed PMID: 15531877.

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Gregory RI, Shiekhattar R. Chromatin modifiers and carcinogenesis. Trends Cell Biol. 2004 Dec;14(12):695-702. doi: 10.1016/j.tcb.2004.10.002. Review. PubMed PMID: 15564046.

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Banting GS, Barak O, Ames TM, Burnham AC, Kardel MD, Cooch NS, Davidson CE, Godbout R, McDermid HE, Shiekhattar R. CECR2, a protein involved in neurulation, forms a novel chromatin remodeling complex with SNF2L. Hum Mol Genet. 2005 Feb 15;14(4):513-24. doi: 10.1093/hmg/ddi048. Epub 2005 Jan 7. PubMed PMID: 15640247.

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Zhou J, Chau CM, Deng Z, Shiekhattar R, Spindler MP, Schepers A, Lieberman PM. Cell cycle regulation of chromatin at an origin of DNA replication. EMBO J. 2005 Apr 6;24(7):1406-17. doi: 10.1038/sj.emboj.7600609. Epub 2005 Mar 17. PubMed PMID: 15775975; PubMed Central PMCID: PMC1142536.

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Guo S, Hakimi MA, Baillat D, Chen X, Farber MJ, Klein-Szanto AJ, Cooch NS, Godwin AK, Shiekhattar R. Linking transcriptional elongation and messenger RNA export to metastatic breast cancers. Cancer Res. 2005 Apr 15;65(8):3011-6. doi: 10.1158/0008-5472.CAN-04-3624. PubMed PMID: 15833825.

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Gregory RI, Shiekhattar R. MicroRNA biogenesis and cancer. Cancer Res. 2005 May 1;65(9):3509-12. doi: 10.1158/0008-5472.CAN-05-0298. Review. PubMed PMID: 15867338.

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Chendrimada TP, Gregory RI, Kumaraswamy E, Norman J, Cooch N, Nishikura K, Shiekhattar R. TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature. 2005 Aug 4;436(7051):740-4. doi: 10.1038/nature03868. Epub 2005 Jun 22. PubMed PMID: 15973356; PubMed Central PMCID: PMC2944926.

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Lee MG, Wynder C, Cooch N, Shiekhattar R. An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation. Nature. 2005 Sep 15;437(7057):432-5. doi: 10.1038/nature04021. Epub 2005 Aug 3. PubMed PMID: 16079794.

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Baillat D, Hakimi MA, Näär AM, Shilatifard A, Cooch N, Shiekhattar R. Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II. Cell. 2005 Oct 21;123(2):265-76. doi: 10.1016/j.cell.2005.08.019. PubMed PMID: 16239144.

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Wynder C, Hakimi MA, Epstein JA, Shilatifard A, Shiekhattar R. Recruitment of MLL by HMG-domain protein iBRAF promotes neural differentiation. Nat Cell Biol. 2005 Nov;7(11):1113-7. doi: 10.1038/ncb1312. PubMed PMID: 16227968.

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Gregory RI, Chendrimada TP, Cooch N, Shiekhattar R. Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell. 2005 Nov 18;123(4):631-40. doi: 10.1016/j.cell.2005.10.022. Epub 2005 Nov 3. PubMed PMID: 16271387.

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Gregory RI, Chendrimada TP, Shiekhattar R. MicroRNA biogenesis: isolation and characterization of the microprocessor complex. Methods Mol Biol. 2006;342:33-47. doi: 10.1385/1-59745-123-1:33. Review. PubMed PMID: 16957365.

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Yang W, Chendrimada TP, Wang Q, Higuchi M, Seeburg PH, Shiekhattar R, Nishikura K. Modulation of microRNA processing and expression through RNA editing by ADAR deaminases. Nat Struct Mol Biol. 2006 Jan;13(1):13-21. doi: 10.1038/nsmb1041. Epub 2005 Dec 20. PubMed PMID: 16369484; PubMed Central PMCID: PMC2950615.

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Da G, Lenkart J, Zhao K, Shiekhattar R, Cairns BR, Marmorstein R. Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2057-62. doi: 10.1073/pnas.0510949103. Epub 2006 Feb 3. PubMed PMID: 16461455; PubMed Central PMCID: PMC1413740.

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Ross DA, Hannenhalli S, Tobias JW, Cooch N, Shiekhattar R, Kadesch T. Functional analysis of Hes-1 in preadipocytes. Mol Endocrinol. 2006 Mar;20(3):698-705. doi: 10.1210/me.2005-0325. Epub 2005 Nov 10. PubMed PMID: 16282371.

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Norman JA, Shiekhattar R. Analysis of Nedd8-associated polypeptides: a model for deciphering the pathway for ubiquitin-like modifications. Biochemistry. 2006 Mar 7;45(9):3014-9. doi: 10.1021/bi052435a. PubMed PMID: 16503656.