My Bibliography

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Telonis AG, Rodriguez DA, Spanheimer PM, Figueroa ME, Goel N. Genetic Ancestry-specific Molecular and Survival Differences in Admixed Patients With Breast Cancer. Ann Surg. 2024 May 1;279(5):866-873. doi: 10.1097/SLA.0000000000006135. Epub 2023 Dec 11. PubMed PMID: 38073557.

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Stahl M, Bewersdorf JP, Xie Z, Porta MGD, Komrokji R, Xu ML, Abdel-Wahab O, Taylor J, Steensma DP, Starczynowski DT, Sekeres MA, Sanz G, Sallman DA, Roboz GJ, Platzbecker U, Patnaik MM, Padron E, Odenike O, Nimer SD, Nazha A, Majeti R, Loghavi S, Little RF, List AF, Kim TK, Hourigan CS, Hasserjian RP, Halene S, Griffiths EA, Gore SD, Greenberg P, Figueroa ME, Fenaux P, Efficace F, DeZern AE, Daver NG, Churpek JE, Carraway HE, Buckstein R, Brunner AM, Boultwood J, Borate U, Bejar R, Bennett JM, Wei AH, Santini V, Savona MR, Zeidan AM. Classification, risk stratification and response assessment in myelodysplastic syndromes/neoplasms (MDS): A state-of-the-art report on behalf of the International Consortium for MDS (icMDS). Blood Rev. 2023 Nov;62:101128. doi: 10.1016/j.blre.2023.101128. Epub 2023 Aug 19. Review. PubMed PMID: 37704469.

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Bewersdorf JP, Xie Z, Bejar R, Borate U, Boultwood J, Brunner AM, Buckstein R, Carraway HE, Churpek JE, Daver NG, Porta MGD, DeZern AE, Fenaux P, Figueroa ME, Gore SD, Griffiths EA, Halene S, Hasserjian RP, Hourigan CS, Kim TK, Komrokji R, Kuchroo VK, List AF, Loghavi S, Majeti R, Odenike O, Patnaik MM, Platzbecker U, Roboz GJ, Sallman DA, Santini V, Sanz G, Sekeres MA, Stahl M, Starczynowski DT, Steensma DP, Taylor J, Abdel-Wahab O, Xu ML, Savona MR, Wei AH, Zeidan AM. Current landscape of translational and clinical research in myelodysplastic syndromes/neoplasms (MDS): Proceedings from the 1(st) International Workshop on MDS (iwMDS) Of the International Consortium for MDS (icMDS). Blood Rev. 2023 Jul;60:101072. doi: 10.1016/j.blre.2023.101072. Epub 2023 Mar 11. Review. PubMed PMID: 36934059.

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Stahl M, Abdel-Wahab O, Wei AH, Savona MR, Xu ML, Xie Z, Taylor J, Starczynowski D, Sanz GF, Sallman DA, Santini V, Roboz GJ, Patnaik MM, Padron E, Odenike O, Nazha A, Nimer SD, Majeti R, Little RF, Gore S, List AF, Kutchroo V, Komrokji RS, Kim TK, Kim N, Hourigan CS, Hasserjian RP, Halene S, Griffiths EA, Greenberg PL, Figueroa M, Fenaux P, Efficace F, DeZern AE, Della Porta MG, Daver NG, Churpek JE, Carraway HE, Brunner AM, Borate U, Bennett JM, Bejar R, Boultwood J, Loghavi S, Bewersdorf JP, Platzbecker U, Steensma DP, Sekeres MA, Buckstein RJ, Zeidan AM. An agenda to advance research in myelodysplastic syndromes: a TOP 10 priority list from the first international workshop in MDS. Blood Adv. 2023 Jun 27;7(12):2709-2714. doi: 10.1182/bloodadvances.2022008747. PubMed PMID: 36260702; PubMed Central PMCID: PMC10333740.

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Goel N, Hernandez A, Thompson C, Choi S, Westrick A, Stoler J, Antoni MH, Rojas K, Kesmodel S, Figueroa ME, Cole S, Merchant N, Kobetz E. Neighborhood Disadvantage and Breast Cancer-Specific Survival. JAMA Netw Open. 2023 Apr 3;6(4):e238908. doi: 10.1001/jamanetworkopen.2023.8908. PubMed PMID: 37083666; PubMed Central PMCID: PMC10122178.

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Brabson JP, Leesang T, Yap YS, Wang J, Lam MQ, Fang B, Dolgalev I, Barbieri DA, Strippoli V, Bañuelos CP, Mohammad S, Lyon P, Chaudhry S, Donich D, Swirski A, Roberts E, Diaz I, Karl D, Dos Santos HG, Shiekhattar R, Neel BG, Nimer SD, Verdun RE, Bilbao D, Figueroa ME, Cimmino L. Oxidized mC modulates synthetic lethality to PARP inhibitors for the treatment of leukemia. Cell Rep. 2023 Jan 31;42(1):112027. doi: 10.1016/j.celrep.2023.112027. Epub 2023 Jan 23. PubMed PMID: 36848231; PubMed Central PMCID: PMC9989506.

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Zeidan AM, Bewersdorf JP, Buckstein R, Sekeres MA, Steensma DP, Platzbecker U, Loghavi S, Boultwood J, Bejar R, Bennett JM, Borate U, Brunner AM, Carraway H, Churpek JE, Daver NG, Della Porta M, DeZern AE, Efficace F, Fenaux P, Figueroa ME, Greenberg P, Griffiths EA, Halene S, Hasserjian RP, Hourigan CS, Kim N, Kim TK, Komrokji RS, Kutchroo V, List AF, Little RF, Majeti R, Nazha A, Nimer SD, Odenike O, Padron E, Patnaik MM, Roboz GJ, Sallman DA, Sanz G, Stahl M, Starczynowski DT, Taylor J, Xie Z, Xu M, Savona MR, Wei AH, Abdel-Wahab O, Santini V. Finding consistency in classifications of myeloid neoplasms: a perspective on behalf of the International Workshop for Myelodysplastic Syndromes. Leukemia. 2022 Dec;36(12):2939-2946. doi: 10.1038/s41375-022-01724-9. Epub 2022 Oct 20. PubMed PMID: 36266326.

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Telonis AG, Yang Q, Huang HT, Figueroa ME. MIR retrotransposons link the epigenome and the transcriptome of coding genes in acute myeloid leukemia. Nat Commun. 2022 Oct 31;13(1):6524. doi: 10.1038/s41467-022-34211-x. PubMed PMID: 36316347; PubMed Central PMCID: PMC9622910.

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Galletta TJ, Loveless SK, Malsch MM, Shimamura A, Myers KC. Coronavirus disease 2019 and vaccination in patients with Shwachman-Diamond syndrome. Pediatr Blood Cancer. 2022 May;69(5):e29647. doi: 10.1002/pbc.29647. Epub 2022 Mar 6. PubMed PMID: 35253346; PubMed Central PMCID: PMC9088415.

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Schaefer EJ, Wang HC, Karp HQ, Meyer CA, Cejas P, Gearhart MD, Adelman ER, Fares I, Apffel A, Lim K, Xie Y, Gibson CJ, Schenone M, Murdock HM, Wang ES, Gondek LP, Carroll MP, Vedula RS, Winer ES, Garcia JS, Stone RM, Luskin MR, Carr SA, Long HW, Bardwell VJ, Figueroa ME, Lindsley RC. BCOR and BCORL1 Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes. Blood Cancer Discov. 2022 Mar 1;3(2):116-135. doi: 10.1158/2643-3230.BCD-21-0115. PubMed PMID: 35015684; PubMed Central PMCID: PMC9414116.

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Pronier E, Imanci A, Selimoglu-Buet D, Badaoui B, Itzykson R, Roger T, Jego C, Naimo A, Francillette M, Breckler M, Wagner-Ballon O, Figueroa ME, Aglave M, Gautheret D, Porteu F, Bernard OA, Vainchenker W, Delhommeau F, Solary E, Droin NM. Macrophage migration inhibitory factor is overproduced through EGR1 in TET2(low) resting monocytes. Commun Biol. 2022 Feb 3;5(1):110. doi: 10.1038/s42003-022-03057-w. PubMed PMID: 35115654; PubMed Central PMCID: PMC8814058.

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Wei Y, Huang YH, Skopelitis DS, Iyer SV, Costa ASH, Yang Z, Kramer M, Adelman ER, Klingbeil O, Demerdash OE, Polyanskaya SA, Chang K, Goodwin S, Hodges E, McCombie WR, Figueroa ME, Vakoc CR. SLC5A3-Dependent Myo-inositol Auxotrophy in Acute Myeloid Leukemia. Cancer Discov. 2022 Feb;12(2):450-467. doi: 10.1158/2159-8290.CD-20-1849. Epub 2021 Sep 16. PubMed PMID: 34531253; PubMed Central PMCID: PMC8831445.

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Man N, Mas G, Karl DL, Sun J, Liu F, Yang Q, Torres-Martin M, Itonaga H, Martinez C, Chen S, Xu Y, Duffort S, Hamard PJ, Chen C, Zucconi BE, Cimmino L, Yang FC, Xu M, Cole PA, Figueroa ME, Nimer SD. p300 suppresses the transition of myelodysplastic syndromes to acute myeloid leukemia. JCI Insight. 2021 Oct 8;6(19). doi: 10.1172/jci.insight.138478. PubMed PMID: 34622806; PubMed Central PMCID: PMC8525640.

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Yang Z, Wu XS, Wei Y, Polyanskaya SA, Iyer SV, Jung M, Lach FP, Adelman ER, Klingbeil O, Milazzo JP, Kramer M, Demerdash OE, Chang K, Goodwin S, Hodges E, McCombie WR, Figueroa ME, Smogorzewska A, Vakoc CR. Transcriptional Silencing of ALDH2 Confers a Dependency on Fanconi Anemia Proteins in Acute Myeloid Leukemia. Cancer Discov. 2021 Sep;11(9):2300-2315. doi: 10.1158/2159-8290.CD-20-1542. Epub 2021 Apr 23. PubMed PMID: 33893150; PubMed Central PMCID: PMC8419016.

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Huang HT, Figueroa ME. Epigenetic deregulation in myeloid malignancies. Blood. 2021 Aug 26;138(8):613-624. doi: 10.1182/blood.2019004262. Review. PubMed PMID: 34436526.

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Sevin M, Debeurme F, Laplane L, Badel S, Morabito M, Newman HL, Torres-Martin M, Yang Q, Badaoui B, Wagner-Ballon O, Saada V, Sélimoglu-Buet D, Kraus-Berthier L, Banquet S, Derreal A, Fenaux P, Itzykson R, Braun T, Etienne G, Berthon C, Thépot S, Kepp O, Kroemer G, Padron E, Figueroa ME, Droin N, Solary E. Cytokine-like protein 1-induced survival of monocytes suggests a combined strategy targeting MCL1 and MAPK in CMML. Blood. 2021 Jun 17;137(24):3390-3402. doi: 10.1182/blood.2020008729. PubMed PMID: 33690800; PubMed Central PMCID: PMC8233685.

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MacBeth KJ, Chopra VS, Tang L, Zheng B, Avanzino B, See WL, Schwickart M, Figueroa ME, Quek L, DiMartino JF. Combination of azacitidine and enasidenib enhances leukemic cell differentiation and cooperatively hypomethylates DNA. Exp Hematol. 2021 Jun;98:47-52.e6. doi: 10.1016/j.exphem.2021.03.003. Epub 2021 Mar 29. PubMed PMID: 33794295.

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Adelman ER, Figueroa ME. Human hematopoiesis: aging and leukemogenic risk. Curr Opin Hematol. 2021 Jan;28(1):57-63. doi: 10.1097/MOH.0000000000000622. Review. PubMed PMID: 33186152; PubMed Central PMCID: PMC7737681.

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Liu S, de Medeiros MC, Fernandez EM, Zarins KR, Cavalcante RG, Qin T, Wolf GT, Figueroa ME, D'Silva NJ, Rozek LS, Sartor MA. 5-Hydroxymethylation highlights the heterogeneity in keratinization and cell junctions in head and neck cancers. Clin Epigenetics. 2020 Nov 17;12(1):175. doi: 10.1186/s13148-020-00965-8. PubMed PMID: 33203436; PubMed Central PMCID: PMC7672859.

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Smith MA, Culver-Cochran AE, Adelman ER, Rhyasen GW, Ma A, Figueroa ME, Starczynowski DT. TNFAIP3 Plays a Role in Aging of the Hematopoietic System. Front Immunol. 2020;11:536442. doi: 10.3389/fimmu.2020.536442. eCollection 2020. PubMed PMID: 33224133; PubMed Central PMCID: PMC7670064.

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Fang C, Wang Z, Han C, Safgren SL, Helmin KA, Adelman ER, Serafin V, Basso G, Eagen KP, Gaspar-Maia A, Figueroa ME, Singer BD, Ratan A, Ntziachristos P, Zang C. Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation. Genome Biol. 2020 Sep 15;21(1):247. doi: 10.1186/s13059-020-02152-7. PubMed PMID: 32933554; PubMed Central PMCID: PMC7493976.

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Balogh P, Adelman ER, Pluvinage JV, Capaldo BJ, Freeman KC, Singh S, Elagib KE, Nakamura Y, Kurita R, Sashida G, Zunder ER, Li H, Gru AA, Price EA, Schrier SL, Weissman IL, Figueroa ME, Pang WW, Goldfarb AN. RUNX3 levels in human hematopoietic progenitors are regulated by aging and dictate erythroid-myeloid balance. Haematologica. 2020 Apr;105(4):905-913. doi: 10.3324/haematol.2018.208918. Epub 2019 Jun 6. PubMed PMID: 31171641; PubMed Central PMCID: PMC7109730.

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Beke A, Laplane L, Riviere J, Yang Q, Torres-Martin M, Dayris T, Rameau P, Saada V, Bilhou-Nabera C, Hurtado A, Lordier L, Vainchenker W, Figueroa ME, Droin N, Solary E. Multilayer intraclonal heterogeneity in chronic myelomonocytic leukemia. Haematologica. 2020 Jan;105(1):112-123. doi: 10.3324/haematol.2018.208488. Epub 2019 May 2. PubMed PMID: 31048357; PubMed Central PMCID: PMC6939510.

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Qin T, Sotzen J, Rampal RK, Rapaport FT, Levine RL, Klimek V, Nimer SD, Figueroa ME. Risk of disease progression in low-risk MDS is linked to distinct epigenetic subtypes. Leukemia. 2019 Nov;33(11):2753-2757. doi: 10.1038/s41375-019-0518-5. Epub 2019 Jul 22. PubMed PMID: 31332268; PubMed Central PMCID: PMC6842085.

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Fernandez AGL, Crescenzi B, Pierini V, Di Battista V, Barba G, Pellanera F, Di Giacomo D, Roti G, Piazza R, Adelman ER, Figueroa ME, Mecucci C. A distinct epigenetic program underlies the 1;7 translocation in myelodysplastic syndromes. Leukemia. 2019 Oct;33(10):2481-2494. doi: 10.1038/s41375-019-0433-9. Epub 2019 Mar 28. PubMed PMID: 30923319; PubMed Central PMCID: PMC7340798.

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Adelman ER, Huang HT, Roisman A, Olsson A, Colaprico A, Qin T, Lindsley RC, Bejar R, Salomonis N, Grimes HL, Figueroa ME. Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia. Cancer Discov. 2019 Aug;9(8):1080-1101. doi: 10.1158/2159-8290.CD-18-1474. Epub 2019 May 13. PubMed PMID: 31085557; PubMed Central PMCID: PMC7080409.

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Núñez FJ, Mendez FM, Kadiyala P, Alghamri MS, Savelieff MG, Garcia-Fabiani MB, Haase S, Koschmann C, Calinescu AA, Kamran N, Saxena M, Patel R, Carney S, Guo MZ, Edwards M, Ljungman M, Qin T, Sartor MA, Tagett R, Venneti S, Brosnan-Cashman J, Meeker A, Gorbunova V, Zhao L, Kremer DM, Zhang L, Lyssiotis CA, Jones L, Herting CJ, Ross JL, Hambardzumyan D, Hervey-Jumper S, Figueroa ME, Lowenstein PR, Castro MG. IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response. Sci Transl Med. 2019 Feb 13;11(479). doi: 10.1126/scitranslmed.aaq1427. PubMed PMID: 30760578; PubMed Central PMCID: PMC6400220.

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Dominguez PM, Ghamlouch H, Rosikiewicz W, Kumar P, Béguelin W, Fontán L, Rivas MA, Pawlikowska P, Armand M, Mouly E, Torres-Martin M, Doane AS, Calvo Fernandez MT, Durant M, Della-Valle V, Teater M, Cimmino L, Droin N, Tadros S, Motanagh S, Shih AH, Rubin MA, Tam W, Aifantis I, Levine RL, Elemento O, Inghirami G, Green MR, Figueroa ME, Bernard OA, Aoufouchi S, Li S, Shaknovich R, Melnick AM. TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis. Cancer Discov. 2018 Dec;8(12):1632-1653. doi: 10.1158/2159-8290.CD-18-0657. Epub 2018 Oct 1. PubMed PMID: 30274972; PubMed Central PMCID: PMC6279514.

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Chan HL, Beckedorff F, Zhang Y, Garcia-Huidobro J, Jiang H, Colaprico A, Bilbao D, Figueroa ME, LaCava J, Shiekhattar R, Morey L. Polycomb complexes associate with enhancers and promote oncogenic transcriptional programs in cancer through multiple mechanisms. Nat Commun. 2018 Aug 23;9(1):3377. doi: 10.1038/s41467-018-05728-x. PubMed PMID: 30139998; PubMed Central PMCID: PMC6107513.

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Jin X, Qin T, Zhao M, Bailey N, Liu L, Yang K, Ng V, Higashimoto T, Coolon R, Ney G, Figueroa ME, Li Q. Oncogenic N-Ras and Tet2 haploinsufficiency collaborate to dysregulate hematopoietic stem and progenitor cells. Blood Adv. 2018 Jun 12;2(11):1259-1271. doi: 10.1182/bloodadvances.2018017400. PubMed PMID: 29866713; PubMed Central PMCID: PMC5998937.

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Santini V, Allione B, Zini G, Gioia D, Lunghi M, Poloni A, Cilloni D, Sanna A, Masiera E, Ceccarelli M, Abdel-Wahab O, Terenzi A, Angelucci E, Finelli C, Onida F, Pelizzari A, Ferrero D, Saglio G, Figueroa M, Levis A. A phase II, multicentre trial of decitabine in higher-risk chronic myelomonocytic leukemia. Leukemia. 2018 Feb;32(2):413-418. doi: 10.1038/leu.2017.186. Epub 2017 Jun 13. PubMed PMID: 28607470; PubMed Central PMCID: PMC5808077.

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Kramer AC, Kothari A, Wilson WC, Celik H, Nikitas J, Mallaney C, Ostrander EL, Eultgen E, Martens A, Valentine MC, Young AL, Druley TE, Figueroa ME, Zhang B, Challen GA. Dnmt3a regulates T-cell development and suppresses T-ALL transformation. Leukemia. 2017 Nov;31(11):2479-2490. doi: 10.1038/leu.2017.89. Epub 2017 Mar 21. PubMed PMID: 28321121; PubMed Central PMCID: PMC5636646.

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Cimmino L, Dolgalev I, Wang Y, Yoshimi A, Martin GH, Wang J, Ng V, Xia B, Witkowski MT, Mitchell-Flack M, Grillo I, Bakogianni S, Ndiaye-Lobry D, Martín MT, Guillamot M, Banh RS, Xu M, Figueroa ME, Dickins RA, Abdel-Wahab O, Park CY, Tsirigos A, Neel BG, Aifantis I. Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression. Cell. 2017 Sep 7;170(6):1079-1095.e20. doi: 10.1016/j.cell.2017.07.032. Epub 2017 Aug 17. PubMed PMID: 28823558; PubMed Central PMCID: PMC5755977.

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Glass JL, Hassane D, Wouters BJ, Kunimoto H, Avellino R, Garrett-Bakelman FE, Guryanova OA, Bowman R, Redlich S, Intlekofer AM, Meydan C, Qin T, Fall M, Alonso A, Guzman ML, Valk PJM, Thompson CB, Levine R, Elemento O, Delwel R, Melnick A, Figueroa ME. Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers. Cancer Discov. 2017 Aug;7(8):868-883. doi: 10.1158/2159-8290.CD-16-1032. Epub 2017 Apr 13. PubMed PMID: 28408400; PubMed Central PMCID: PMC5540802.

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Ho TT, Warr MR, Adelman ER, Lansinger OM, Flach J, Verovskaya EV, Figueroa ME, Passegué E. Autophagy maintains the metabolism and function of young and old stem cells. Nature. 2017 Mar 9;543(7644):205-210. doi: 10.1038/nature21388. Epub 2017 Mar 1. PubMed PMID: 28241143; PubMed Central PMCID: PMC5344718.

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Luskin MR, Gimotty PA, Smith C, Loren AW, Figueroa ME, Harrison J, Sun Z, Tallman MS, Paietta EM, Litzow MR, Melnick AM, Levine RL, Fernandez HF, Luger SM, Carroll M, Master SR, Wertheim GB. A clinical measure of DNA methylation predicts outcome in de novo acute myeloid leukemia. JCI Insight. 2016 Jun 16;1(9). doi: 10.1172/jci.insight.87323. PubMed PMID: 27446991; PubMed Central PMCID: PMC4951094.

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Rampal R, Figueroa ME. Wilms tumor 1 mutations in the pathogenesis of acute myeloid leukemia. Haematologica. 2016 Jun;101(6):672-9. doi: 10.3324/haematol.2015.141796. Review. PubMed PMID: 27252512; PubMed Central PMCID: PMC5013955.

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Meyer SE, Qin T, Muench DE, Masuda K, Venkatasubramanian M, Orr E, Suarez L, Gore SD, Delwel R, Paietta E, Tallman MS, Fernandez H, Melnick A, Le Beau MM, Kogan S, Salomonis N, Figueroa ME, Grimes HL. DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia. Cancer Discov. 2016 May;6(5):501-15. doi: 10.1158/2159-8290.CD-16-0008. Epub 2016 Mar 25. PubMed PMID: 27016502; PubMed Central PMCID: PMC4861898.

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Merlevede J, Droin N, Qin T, Meldi K, Yoshida K, Morabito M, Chautard E, Auboeuf D, Fenaux P, Braun T, Itzykson R, de Botton S, Quesnel B, Commes T, Jourdan E, Vainchenker W, Bernard O, Pata-Merci N, Solier S, Gayevskiy V, Dinger ME, Cowley MJ, Selimoglu-Buet D, Meyer V, Artiguenave F, Deleuze JF, Preudhomme C, Stratton MR, Alexandrov LB, Padron E, Ogawa S, Koscielny S, Figueroa M, Solary E. Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents. Nat Commun. 2016 Feb 24;7:10767. doi: 10.1038/ncomms10767. PubMed PMID: 26908133; PubMed Central PMCID: PMC4770084.

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Prebet T, Sun Z, Ketterling RP, Zeidan A, Greenberg P, Herman J, Juckett M, Smith MR, Malick L, Paietta E, Czader M, Figueroa M, Gabrilove J, Erba HP, Tallman MS, Litzow M, Gore SD. Azacitidine with or without Entinostat for the treatment of therapy-related myeloid neoplasm: further results of the E1905 North American Leukemia Intergroup study. Br J Haematol. 2016 Feb;172(3):384-91. doi: 10.1111/bjh.13832. Epub 2015 Nov 18. PubMed PMID: 26577691; PubMed Central PMCID: PMC4794257.

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Gaillard C, Tokuyasu TA, Rosen G, Sotzen J, Vitaliano-Prunier A, Roy R, Passegué E, de Thé H, Figueroa ME, Kogan SC. Transcription and methylation analyses of preleukemic promyelocytes indicate a dual role for PML/RARA in leukemia initiation. Haematologica. 2015 Aug;100(8):1064-75. doi: 10.3324/haematol.2014.123018. Epub 2015 Jun 18. PubMed PMID: 26088929; PubMed Central PMCID: PMC5004423.

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Meldi KM, Figueroa ME. Cytosine modifications in myeloid malignancies. Pharmacol Ther. 2015 Aug;152:42-53. doi: 10.1016/j.pharmthera.2015.05.002. Epub 2015 May 5. Review. PubMed PMID: 25956466.

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Amabile G, Di Ruscio A, Müller F, Welner RS, Yang H, Ebralidze AK, Zhang H, Levantini E, Qi L, Martinelli G, Brummelkamp T, Le Beau MM, Figueroa ME, Bock C, Tenen DG. Dissecting the role of aberrant DNA methylation in human leukaemia. Nat Commun. 2015 May 22;6:7091. doi: 10.1038/ncomms8091. PubMed PMID: 25997600; PubMed Central PMCID: PMC4443494.

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Meldi K, Qin T, Buchi F, Droin N, Sotzen J, Micol JB, Selimoglu-Buet D, Masala E, Allione B, Gioia D, Poloni A, Lunghi M, Solary E, Abdel-Wahab O, Santini V, Figueroa ME. Specific molecular signatures predict decitabine response in chronic myelomonocytic leukemia. J Clin Invest. 2015 May;125(5):1857-72. doi: 10.1172/JCI78752. Epub 2015 Mar 30. PubMed PMID: 25822018; PubMed Central PMCID: PMC4611703.

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Park SM, Gönen M, Vu L, Minuesa G, Tivnan P, Barlowe TS, Taggart J, Lu Y, Deering RP, Hacohen N, Figueroa ME, Paietta E, Fernandez HF, Tallman MS, Melnick A, Levine R, Leslie C, Lengner CJ, Kharas MG. Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program. J Clin Invest. 2015 Mar 2;125(3):1286-98. doi: 10.1172/JCI78440. Epub 2015 Feb 9. PubMed PMID: 25664853; PubMed Central PMCID: PMC4362230.

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Garrett-Bakelman FE, Sheridan CK, Kacmarczyk TJ, Ishii J, Betel D, Alonso A, Mason CE, Figueroa ME, Melnick AM. Enhanced reduced representation bisulfite sequencing for assessment of DNA methylation at base pair resolution. J Vis Exp. 2015 Feb 24;(96):e52246. doi: 10.3791/52246. PubMed PMID: 25742437; PubMed Central PMCID: PMC4354670.

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Meldi KM, Figueroa ME. Epigenetic deregulation in myeloid malignancies. Transl Res. 2015 Jan;165(1):102-14. doi: 10.1016/j.trsl.2014.04.012. Epub 2014 Apr 24. Review. PubMed PMID: 24813528.

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Gölzenleuchter M, Kanwar R, Zaibak M, Al Saiegh F, Hartung T, Klukas J, Smalley RL, Cunningham JM, Figueroa ME, Schroth GP, Therneau TM, Banck MS, Beutler AS. Plasticity of DNA methylation in a nerve injury model of pain. Epigenetics. 2015;10(3):200-12. doi: 10.1080/15592294.2015.1006493. PubMed PMID: 25621511; PubMed Central PMCID: PMC4622653.

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Wertheim GB, Smith C, Luskin M, Rager A, Figueroa ME, Carroll M, Master SR. Validation of DNA methylation to predict outcome in acute myeloid leukemia by use of xMELP. Clin Chem. 2015 Jan;61(1):249-58. doi: 10.1373/clinchem.2014.229781. Epub 2014 Oct 27. PubMed PMID: 25348669; PubMed Central PMCID: PMC4384518.

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Rampal R, Alkalin A, Madzo J, Vasanthakumar A, Pronier E, Patel J, Li Y, Ahn J, Abdel-Wahab O, Shih A, Lu C, Ward PS, Tsai JJ, Hricik T, Tosello V, Tallman JE, Zhao X, Daniels D, Dai Q, Ciminio L, Aifantis I, He C, Fuks F, Tallman MS, Ferrando A, Nimer S, Paietta E, Thompson CB, Licht JD, Mason CE, Godley LA, Melnick A, Figueroa ME, Levine RL. DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia. Cell Rep. 2014 Dec 11;9(5):1841-1855. doi: 10.1016/j.celrep.2014.11.004. Epub 2014 Dec 4. PubMed PMID: 25482556; PubMed Central PMCID: PMC4267494.