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Nisenbaum E, Wiefels M, Telischi J, Marasigan M, Kanumuri V, Pena S, Thielhelm T, Bracho O, Bhatia R, Scaglione T, Telischi F, Fernandez-Valle C, Liu XZ, Luther E, Morcos J, Ivan M, Dinh CT. Cytokine Profiling of Cyst Fluid and Tumor-Associated Macrophages in Cystic Vestibular Schwannoma. Otol Neurotol. 2023 Dec 1;44(10):1073-1081. doi: 10.1097/MAO.0000000000004032. Epub 2023 Oct 19. PubMed PMID: 37853737; PubMed Central PMCID: PMC10669777.
Khan NR, Elarjani T, Jamshidi AM, Chen SH, Brown CS, Abecassis J, Silva MA, Lu VM, Wu E, Diaz-Kanelidis M, Bhatia R, Hoffer ME, Eshraghi AA, Dinh CT, Angeli SI, Telischi FF, Morcos JJ. Microsurgical Management of Vestibular Schwannoma (Acoustic Neuroma): Facial Nerve Outcomes, Radiographic Analysis, Complications, and Long-Term Follow-Up in a Series of 420 Surgeries. World Neurosurg. 2022 Dec;168:e297-e308. doi: 10.1016/j.wneu.2022.09.125. Epub 2022 Oct 2. PubMed PMID: 36198364.
Thielhelm TP, Nourbakhsh A, Welford SM, Mellon EA, Bracho O, Ivan ME, Telischi F, Fernandez-Valle C, Dinh CT. RAD51 Inhibitor and Radiation Toxicity in Vestibular Schwannoma. Otolaryngol Head Neck Surg. 2022 Nov;167(5):860-868. doi: 10.1177/01945998221083506. Epub 2022 Mar 1. PubMed PMID: 35230908; PubMed Central PMCID: PMC9433467.
Cohen ER, Misztal C, Dable C, Gomez-Fernandez C, Bhatia RG, Roth P, Ma R, Trosman S, Green C, Nicolli E, Dinh CT, Sargi ZB. Redefining Perineural Invasion in Head and Neck Cutaneous Squamous Cell Carcinoma. Otolaryngol Head Neck Surg. 2022 Oct;167(4):705-715. doi: 10.1177/01945998221076110. Epub 2022 Feb 8. PubMed PMID: 35133896.
Thielhelm TP, Dinh CT, Sargi Z, Ivan ME, Ein L. Haller's Ansa: An Unrecognized Route of Facial Movement After Skull Base Surgery. Laryngoscope. 2022 Sep;132(9):1750-1752. doi: 10.1002/lary.29932. Epub 2021 Nov 6. Review. PubMed PMID: 34741465.
Huegel J, Dinh CT, Martinelli M, Bracho O, Rosario R, Hardin H, Estivill M, Griswold A, Gultekin S, Liu XZ, Fernandez-Valle C. CUDC907, a dual phosphoinositide-3 kinase/histone deacetylase inhibitor, promotes apoptosis of NF2 Schwannoma cells. Oncotarget. 2022;13:890-904. doi: 10.18632/oncotarget.28254. eCollection 2022. PubMed PMID: 35875610; PubMed Central PMCID: PMC9295707.
Misztal C, Bracho O, Bas E, Estivill M, Ivan ME, Morcos J, Bhatia R, Telischi F, Liu XZ, Gultekin SH, Fernandez-Valle C, Dinh CT. Effect of AR42 in Primary Vestibular Schwannoma Cells and a Xenograft Model of Vestibular Schwannoma. Otol Neurotol. 2022 Jul 1;43(6):694-701. doi: 10.1097/MAO.0000000000003556. PubMed PMID: 35761463; PubMed Central PMCID: PMC9354971.
Allaf A, Victoria B, Rosario R, Misztal C, Humayun Gultekin S, Dinh CT, Fernandez-Valle C. WP1066 induces cell death in a schwannomatosis patient-derived schwannoma cell line. Cold Spring Harb Mol Case Stud. 2022 Jun;8(4). doi: 10.1101/mcs.a006178. Print 2022 Jun. PubMed PMID: 35732500; PubMed Central PMCID: PMC9235848.
Cohen E, Pena S, Mei C, Bracho O, Marples B, Elsayyad N, Goncalves S, Ivan M, Monje PV, Liu XZ, Fernandez-Valle C, Telischi F, Dinh CT. Merlin-Deficient Schwann Cells Are More Susceptible to Radiation Injury than Normal Schwann Cells In Vitro. J Neurol Surg B Skull Base. 2022 Jun;83(3):228-236. doi: 10.1055/s-0040-1722283. eCollection 2022 Jun. PubMed PMID: 35769808; PubMed Central PMCID: PMC9236706.
Misztal C, Peña S, Martinez D, Velandia S, Goncalves S, Ma R, Holcomb M, Angeli S, Telischi F, Dinh CT. Comparison of Speech Test Outcomes After Cochlear Implantation in Patients With and Without Asymmetric Hearing Loss. Otol Neurotol. 2022 Jun 1;43(5):559-566. doi: 10.1097/MAO.0000000000003515. Epub 2022 Mar 8. PubMed PMID: 35261377.
Cohen ER, Peña S, Misztal C, Iglesias T, Alejandro M, Dinh CT, Holt G, Thomas GR. N95 vs Half-face Respirator Wear in Surgical Trainees: Physiologic and Psychological Effects of Prolonged Use. OTO Open. 2021 Oct-Dec;5(4):2473974X211065437. doi: 10.1177/2473974X211065437. eCollection 2021 Oct-Dec. PubMed PMID: 34926978; PubMed Central PMCID: PMC8671672.
Thielhelm TP, Goncalves S, Welford S, Mellon EA, Bracho O, Estivill M, Brown C, Morcos J, Ivan ME, Telischi F, Fernandez-Valle C, Dinh CT. Primary Vestibular Schwannoma Cells Activate p21 and RAD51-Associated DNA Repair Following Radiation-Induced DNA Damage. Otol Neurotol. 2021 Dec 1;42(10):e1600-e1608. doi: 10.1097/MAO.0000000000003322. PubMed PMID: 34420024; PubMed Central PMCID: PMC8595670.
Misztal CI, Green C, Mei C, Bhatia R, Velez Torres JM, Kamrava B, Moon S, Nicolli E, Weed D, Sargi Z, Dinh CT. Molecular and Cellular Mechanisms of Perineural Invasion in Oral Squamous Cell Carcinoma: Potential Targets for Therapeutic Intervention. Cancers (Basel). 2021 Nov 29;13(23). doi: 10.3390/cancers13236011. Review. PubMed PMID: 34885121; PubMed Central PMCID: PMC8656475.
Nisenbaum E, Misztal C, Szczupak M, Thielhelm T, Peña S, Mei C, Goncalves S, Bracho O, Ma R, Ivan ME, Morcos J, Telischi F, Liu XZ, Fernandez-Valle C, Dinh CT. Tumor-Associated Macrophages in Vestibular Schwannoma and Relationship to Hearing. OTO Open. 2021 Oct-Dec;5(4):2473974X211059111. doi: 10.1177/2473974X211059111. eCollection 2021 Oct-Dec. PubMed PMID: 34870062; PubMed Central PMCID: PMC8638079.
Luther E, Kaur G, Komotar R, Dinh C, Ivan ME. Commentary: Interposition Grafting of the Facial Nerve After Resection of a Large Facial Nerve Schwannoma: 2-Dimensional Operative Video. Oper Neurosurg (Hagerstown). 2021 Sep 15;21(4):E342-E343. doi: 10.1093/ons/opab254. PubMed PMID: 34235543.
Thielhelm TP, Goncalves S, Welford SM, Mellon EA, Cohen ER, Nourbakhsh A, Fernandez-Valle C, Telischi F, Ivan ME, Dinh CT. Understanding the Radiobiology of Vestibular Schwannomas to Overcome Radiation Resistance. Cancers (Basel). 2021 Sep 12;13(18). doi: 10.3390/cancers13184575. Review. PubMed PMID: 34572805; PubMed Central PMCID: PMC8467596.
Szczupak M, Peña SA, Bracho O, Mei C, Bas E, Fernandez-Valle C, Liu XZ, Telischi FF, Ivan M, Dinh CT. Fluorescent Detection of Vestibular Schwannoma Using Intravenous Sodium Fluorescein In Vivo. Otol Neurotol. 2021 Apr 1;42(4):e503-e511. doi: 10.1097/MAO.0000000000002988. PubMed PMID: 33492057; PubMed Central PMCID: PMC8590806.
Mittal R, Bencie N, Liu G, Eshraghi N, Nisenbaum E, Blanton SH, Yan D, Mittal J, Dinh CT, Young JI, Gong F, Liu XZ. Recent advancements in understanding the role of epigenetics in the auditory system. Gene. 2020 Nov 30;761:144996. doi: 10.1016/j.gene.2020.144996. Epub 2020 Jul 29. Review. PubMed PMID: 32738421; PubMed Central PMCID: PMC8168289.
Velandia S, Martinez D, Goncalves S, Pena S, Bas E, Ein L, Prentiss S, Telischi F, Angeli S, Dinh CT. Effect of age, electrode array, and time on cochlear implant impedances. Cochlear Implants Int. 2020 Nov;21(6):344-352. doi: 10.1080/14670100.2020.1788859. Epub 2020 Jul 8. PubMed PMID: 32640889.
Dinh CT, Nisenbaum E, Chyou D, Misztal C, Yan D, Mittal R, Young J, Tekin M, Telischi F, Fernandez-Valle C, Liu XZ. Genomics, Epigenetics, and Hearing Loss in Neurofibromatosis Type 2. Otol Neurotol. 2020 Jun;41(5):e529-e537. doi: 10.1097/MAO.0000000000002613. Review. PubMed PMID: 32150022; PubMed Central PMCID: PMC7547625.
Ein L, Bracho O, Mei C, Patel J, Boyle T, Monje P, Fernandez-Valle C, Bas E, Thomas G, Weed D, Sargi Z, Dinh C. Inhibition of tropomyosine receptor kinase B on the migration of human Schwann cell and dispersion of oral tongue squamous cell carcinoma in vitro. Head Neck. 2019 Dec;41(12):4069-4075. doi: 10.1002/hed.25956. Epub 2019 Sep 9. PubMed PMID: 31497919.
Ein L, Mei C, Bracho O, Bas E, Monje P, Weed D, Sargi Z, Thomas G, Dinh C. Modulation of BDNF-TRKB Interactions on Schwann Cell-induced Oral Squamous Cell Carcinoma Dispersion In Vitro. Anticancer Res. 2019 Nov;39(11):5933-5942. doi: 10.21873/anticanres.13798. PubMed PMID: 31704818.
Bas E, Anwar MR, Goncalves S, Dinh CT, Bracho OR, Chiossone JA, Van De Water TR. Laminin-coated electrodes improve cochlear implant function and post-insertion neuronal survival. Neuroscience. 2019 Jul 1;410:97-107. doi: 10.1016/j.neuroscience.2019.04.048. Epub 2019 May 3. PubMed PMID: 31059743.
Fuse MA, Dinh CT, Vitte J, Kirkpatrick J, Mindos T, Plati SK, Young JI, Huang J, Carlstedt A, Franco MC, Brnjos K, Nagamoto J, Petrilli AM, Copik AJ, Soulakova JN, Bracho O, Yan D, Mittal R, Shen R, Telischi FF, Morrison H, Giovannini M, Liu XZ, Chang LS, Fernandez-Valle C. Preclinical assessment of MEK1/2 inhibitors for neurofibromatosis type 2-associated schwannomas reveals differences in efficacy and drug resistance development. Neuro Oncol. 2019 Mar 18;21(4):486-497. doi: 10.1093/neuonc/noz002. PubMed PMID: 30615146; PubMed Central PMCID: PMC6422635.
Perez ER, Bracho O, Ein L, Szczupak M, Monje PV, Fernandez-Valle C, Alshaiji A, Ivan M, Morcos J, Liu XZ, Hoffer M, Eshraghi A, Angeli S, Telischi F, Dinh CT. Fluorescent Detection of Merlin-deficient Schwann Cells and Primary Human Vestibular Schwannoma Cells Using Sodium Fluorescein. Otol Neurotol. 2018 Sep;39(8):1053-1059. doi: 10.1097/MAO.0000000000001895. PubMed PMID: 30001282; PubMed Central PMCID: PMC6095714.
Dinh CT, Bracho O, Mei C, Bas E, Fernandez-Valle C, Telischi F, Liu XZ. A Xenograft Model of Vestibular Schwannoma and Hearing Loss. Otol Neurotol. 2018 Jun;39(5):e362-e369. doi: 10.1097/MAO.0000000000001766. PubMed PMID: 29557843; PubMed Central PMCID: PMC5940567.
Fuse MA, Plati SK, Burns SS, Dinh CT, Bracho O, Yan D, Mittal R, Shen R, Soulakova JN, Copik AJ, Liu XZ, Telischi FF, Chang LS, Franco MC, Fernandez-Valle C. Combination Therapy with c-Met and Src Inhibitors Induces Caspase-Dependent Apoptosis of Merlin-Deficient Schwann Cells and Suppresses Growth of Schwannoma Cells. Mol Cancer Ther. 2017 Nov;16(11):2387-2398. doi: 10.1158/1535-7163.MCT-17-0417. Epub 2017 Aug 3. PubMed PMID: 28775147.
Petrilli AM, Garcia J, Bott M, Klingeman Plati S, Dinh CT, Bracho OR, Yan D, Zou B, Mittal R, Telischi FF, Liu XZ, Chang LS, Welling DB, Copik AJ, Fernández-Valle C. Ponatinib promotes a G1 cell-cycle arrest of merlin/NF2-deficient human schwann cells. Oncotarget. 2017 May 9;8(19):31666-31681. doi: 10.18632/oncotarget.15912. PubMed PMID: 28427224; PubMed Central PMCID: PMC5458238.
Dinh CT, Chen S, Dinh J, Goncalves S, Bas E, Padgett K, Johnson P, Elsayyad N, Telischi F, Van De Water T. Effects of Intratympanic Dexamethasone on High-Dose Radiation Ototoxicity In Vivo. Otol Neurotol. 2017 Feb;38(2):180-186. doi: 10.1097/MAO.0000000000001289. PubMed PMID: 27898607.
Bas E, Bohorquez J, Goncalves S, Perez E, Dinh CT, Garnham C, Hessler R, Eshraghi AA, Van De Water TR. Electrode array-eluted dexamethasone protects against electrode insertion trauma induced hearing and hair cell losses, damage to neural elements, increases in impedance and fibrosis: A dose response study. Hear Res. 2016 Jul;337:12-24. doi: 10.1016/j.heares.2016.02.003. Epub 2016 Feb 15. PubMed PMID: 26892906.
Dinh CT, Goncalves S, Bhatia R, Truong K, Telischi F, Angeli S, Morcos J, Eshraghi AA. Atypical radiographic features of skull base cholesterol granuloma. Eur Arch Otorhinolaryngol. 2016 Jun;273(6):1425-31. doi: 10.1007/s00405-015-3705-7. Epub 2015 Jul 12. PubMed PMID: 26164292.
Dinh C, Chen S, Padgett K, Dinh J, Telischi F, Elsayyad N, Johnson P, Angeli S, Bas E, Goncalves S, Eshraghi A, Van De Water T. Dexamethasone Protects Against Radiation-induced Loss of Auditory Hair Cells In Vitro. Otol Neurotol. 2015 Dec;36(10):1741-7. doi: 10.1097/MAO.0000000000000850. PubMed PMID: 26485588.
Dinh CT, Chen S, Bas E, Dinh J, Goncalves S, Telischi F, Angeli S, Eshraghi AA, Van De Water T. Dexamethasone Protects Against Apoptotic Cell Death of Cisplatin-exposed Auditory Hair Cells In Vitro. Otol Neurotol. 2015 Sep;36(9):1566-71. doi: 10.1097/MAO.0000000000000849. PubMed PMID: 26375980.
Bas E, Goncalves S, Adams M, Dinh CT, Bas JM, Van De Water TR, Eshraghi AA. Spiral ganglion cells and macrophages initiate neuro-inflammation and scarring following cochlear implantation. Front Cell Neurosci. 2015;9:303. doi: 10.3389/fncel.2015.00303. eCollection 2015. PubMed PMID: 26321909; PubMed Central PMCID: PMC4532929.
Dinh C, Szczupak M, Moon S, Angeli S, Eshraghi A, Telischi FF. Human Temporal Bone Removal: The Skull Base Block Method. J Neurol Surg B Skull Base. 2015 Aug;76(4):278-80. doi: 10.1055/s-0034-1543972. Epub 2015 Mar 2. PubMed PMID: 26225316; PubMed Central PMCID: PMC4516741.
Dinh CT, Goncalves S, Bas E, Van De Water TR, Zine A. Molecular regulation of auditory hair cell death and approaches to protect sensory receptor cells and/or stimulate repair following acoustic trauma. Front Cell Neurosci. 2015;9:96. doi: 10.3389/fncel.2015.00096. eCollection 2015. Review. PubMed PMID: 25873860; PubMed Central PMCID: PMC4379916.
Dinh C, Bas E, Dinh J, Vu L, Gupta C, Van De Water TR. Short interfering RNA against Bax attenuates TNFα-induced ototoxicity in rat organ of Corti explants. Otolaryngol Head Neck Surg. 2013 May;148(5):834-40. doi: 10.1177/0194599813477631. Epub 2013 Feb 11. PubMed PMID: 23401256.
Bas E, Dinh CT, Garnham C, Polak M, Van de Water TR. Conservation of hearing and protection of hair cells in cochlear implant patients' with residual hearing. Anat Rec (Hoboken). 2012 Nov;295(11):1909-27. doi: 10.1002/ar.22574. Epub 2012 Oct 8. Review. PubMed PMID: 23044907.
Dinh CT, Bas E, Chan SS, Dinh JN, Vu L, Van De Water TR. Dexamethasone treatment of tumor necrosis factor-alpha challenged organ of Corti explants activates nuclear factor kappa B signaling that induces changes in gene expression that favor hair cell survival. Neuroscience. 2011 Aug 11;188:157-67. doi: 10.1016/j.neuroscience.2011.04.061. Epub 2011 May 7. PubMed PMID: 21571041.
Castilla DM, Dinh CT, Younis R. Pediatric airway management in craniofacial trauma. J Craniofac Surg. 2011 Jul;22(4):1175-8. doi: 10.1097/SCS.0b013e31821c00c3. PubMed PMID: 21778839.
Eshraghi AA, Dinh CT, Bohorquez J, Angeli S, Abi-Hachem R, Van De Water TR. Local drug delivery to conserve hearing: mechanisms of action of eluted dexamethasone within the cochlea. Cochlear Implants Int. 2011 May;12 Suppl 1:S51-3. doi: 10.1179/146701011X13001035753254. PubMed PMID: 21756473.
Eshraghi AA, Hoosien G, Ramsay S, Dinh CT, Bas E, Balkany TJ, Van De Water TR. Inhibition of the JNK signal cascade conserves hearing against electrode insertion trauma-induced loss. Cochlear Implants Int. 2010 Jun;11 Suppl 1:104-9. doi: 10.1179/146701010x12671177544104. PubMed PMID: 21756592.
Van De Water TR, Abi Hachem RN, Dinh CT, Bas E, Haake SM, Hoosien G, Vivero R, Chan S, He J, Eshraghi AA, Angeli SI, Telischi FF, Balkany TJ. Conservation of hearing and protection of auditory hair cells against trauma-induced losses by local dexamethasone therapy: molecular and genetic mechanisms. Cochlear Implants Int. 2010 Jun;11 Suppl 1:42-55. doi: 10.1179/146701010X12671178390834. PubMed PMID: 21756583.
van de Water TR, Dinh CT, Vivero R, Hoosien G, Eshraghi AA, Balkany TJ. Mechanisms of hearing loss from trauma and inflammation: otoprotective therapies from the laboratory to the clinic. Acta Otolaryngol. 2010 Mar;130(3):308-11. doi: 10.1080/00016480903124655. Review. PubMed PMID: 19579145.
Hoang KN, Dinh CT, Bas E, Chen S, Eshraghi AA, Van De Water TR. Dexamethasone treatment of naïve organ of Corti explants alters the expression pattern of apoptosis-related genes. Brain Res. 2009 Dec 8;1301:1-8. doi: 10.1016/j.brainres.2009.08.097. Epub 2009 Sep 9. PubMed PMID: 19747459.
Dinh CT, Van De Water TR. Blocking pro-cell-death signal pathways to conserve hearing. Audiol Neurootol. 2009;14(6):383-92. doi: 10.1159/000241895. Epub 2009 Nov 16. Review. PubMed PMID: 19923808.
Haake SM, Dinh CT, Chen S, Eshraghi AA, Van De Water TR. Dexamethasone protects auditory hair cells against TNFalpha-initiated apoptosis via activation of PI3K/Akt and NFkappaB signaling. Hear Res. 2009 Sep;255(1-2):22-32. doi: 10.1016/j.heares.2009.05.003. Epub 2009 May 13. PubMed PMID: 19442713.
Dinh CT, Haake S, Chen S, Hoang K, Nong E, Eshraghi AA, Balkany TJ, Van De Water TR. Dexamethasone protects organ of corti explants against tumor necrosis factor-alpha-induced loss of auditory hair cells and alters the expression levels of apoptosis-related genes. Neuroscience. 2008 Nov 19;157(2):405-13. doi: 10.1016/j.neuroscience.2008.09.012. Epub 2008 Sep 11. PubMed PMID: 18838114.
Dinh C, Hoang K, Haake S, Chen S, Angeli S, Nong E, Eshraghi AA, Balkany TJ, Van De Water TR. Biopolymer-released dexamethasone prevents tumor necrosis factor alpha-induced loss of auditory hair cells in vitro: implications toward the development of a drug-eluting cochlear implant electrode array. Otol Neurotol. 2008 Oct;29(7):1012-9. doi: 10.1097/MAO.0b013e3181859a1f. PubMed PMID: 18818545.
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