Feng-Chun Yang, M.D., Ph.D.
- Biochemistry & Molecular Biology
Dr. Yang’s laboratory has been focused on investigating the underlying mechanism of hematopoietic malignancies, with a specific focus on the role of ASXL family, BAP1, and NF1 in the pathogenesis of myeloid malignancies. Alteration of ASXL family genes are in multiple forms of myeloid malignancies, including myelodysplastic syndrome (MDS), myeloproliferative neoplasms (MPN), MDS/MPN (such as CMML and JMML), and acute myeloid leukemia (AML). However, the role of ASXL1 in the pathogenesis of myeloid malignancies and in normal hematopoiesis remains largely.