Contact Information
Office:
(305)243-3668
Batchelor Building 4th Fl (D8-4)
Email
sshin@med.miami.edu
Seung-Uon U. Shin, Ph.D.
- Research Associate Professor
Department:
- Medicine
Research Interest
Dr. Shin has developed novel reagents designed to target micrometastatic disease. His long term research goal has been to develop therapeutic anti-tumor antibody fusion proteins, which employ the targeting flexibility of antibodies to direct localization of biological active molecules to the tumor site, and to investigate potential mechanisms of anti-tumor efficacy. He will study mechanisms by which antibody-endostatin fusion proteins inhibit angiogenesis and/or vasculogenic mimicry (VM) which may contribute to the formation of capillary like vascular channel structures in tumors, and whether antibody-endostatin fusion proteins used will prove more effective in tumors.