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Hudson Lab

Inflammation in metastatic disease

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Investigator / Contact Person Barry Hudson

Research Focus

My research is focused on: (1) how inflammation increases breast cancer metastasis, and (2) how inflammatory comorbidities including obesity and diabetes drives breast cancer progression and metastasis. Specifically, my work focuses on the Receptor for Advanced Glycation End-products (RAGE) and its ligands that participate in many malignant states including breast cancer. We have found RAGE promotes breast cancer progression and metastasis and have developed novel therapeutic approaches to target RAGE. We are currently performing preclinical studies with RAGE inhibitors in order to translate these findings to clinical trials in women with aggressive and metastatic cancer. 

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