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Ahmad Lab

Lipid Metabolism, Normal Tissue Toxicity, and Tumor Resistance

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Investigator / Contact Person Anis Ahmad, Ph.D.

Research Focus

Dr. Ahmad's laboratory investigates the mechanisms responsible for chemotherapeutic drugs and radiation therapy-induced normal tissue toxicity. The group is interested in understanding how disrupted lipid metabolism contributes to renal injury, leading to end-stage renal disease (ESRD), and fosters treatment resistance in cancer cells. The lab employs murine models of hematopoietic stem cell transplantation (HSCT) and renal cancer to explore the effects of dysregulated lipid metabolism on renal injuries and treatment resistance. Ultimately, their goal is to identify novel therapeutic pathways and targets that can enhance treatment outcomes and improve the quality of life for cancer survivors.

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