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  • Adherence to Electrical Glossal In Situ Stimulation for Sleep Apnea (AEGIS Study)

Adherence to Electrical Glossal In Situ Stimulation for Sleep Apnea (AEGIS Study)

Principal Investigator

Naresh Punjabi

Enrollment Status

Closed

Clinical Trial ID

Institutional Protocol # 20210068
National Clinical Trials Identifier NCT04974515

Clinical Trial Summary

The purpose of this research is to assess how well people with mild obstructive sleep apnea
(OSA) adhere to the eXciteOSA device and specifically examine whether adherence of the device
is different with low versus high electrical stimulation. In addition, this research study
will assess how well the device affects mild sleep apnea and if it improves sleepiness and
quality of life.


Phase

N/A


Funding Agency/Sponsor

Other


Disease

Other


Enrollment Eligibility

Inclusion Criteria:
1. Age greater than 18 years
2. Ability to consent
3. Home sleep apnea test demonstrating mild obstructive sleep apnea.
4. Smartphone or tablet
Exclusion Criteria:
1. Current pacemaker, defibrillator, or neuro-stimulation device
2. No prior oropharyngeal surgery for sleep apnea
3. No implants, metal prostheses, dental braces, or soft tissue/bony ulcerations in the
oral cavity
4. No prior use of mandibular advancement device (MAD) or continuous positive airway
pressure (CPAP)
5. Heart failure (New York Heart Association Class 3 or 4; or ejection fraction < 45%)
6. Active coronary disease defined as an intervention (e.g., angioplasty, coronary artery
bypass surgery) in the prior 6 months
7. Uncontrolled hypertension (BP > 160/100)
8. Clinician diagnosis of any chronic lung disease except asthma
9. Chronic fatigue syndrome or fibromyalgia
10. Self-reported current illicit drug use in the past 30 days
11. Self-reported use of marijuana or opiates in the past 30 days
12. Use of supplemental oxygen
13. Self-reported use of prescribed or over the counter sleeping medications in the past
30 days
14. Current pregnancy or intention of becoming pregnant
15. Oropharyngeal abnormalities (class 2 or class 3 malocclusion)
16. Periodic breathing (Cheyne Stoke respiration)
17. Central sleep apnea (central apnea index (CAI) > 5/h)
18. Investigator discretion
19. Prisoners


Contact Information

Study Contact Naresh Punjabi
Phone Number
Email nmp136@miami.edu
Get detailed information on ClinicalTrials.Gov

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