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  • Evaluation of Patient Outcomes From the Kidney Allograft Outcomes AlloSure Registry

Evaluation of Patient Outcomes From the Kidney Allograft Outcomes AlloSure Registry

Principal Investigator

George Burke

Enrollment Status

Not Accepting

Clinical Trial ID

Institutional Protocol # 20191022
National Clinical Trials Identifier NCT03326076

Clinical Trial Summary

This is an observational study to evaluate safety and efficacy outcomes in renal transplant
recipients in whom post-transplant care is managed using AlloSure®. AlloSure® is a
non-invasive test to measure donor-derived cell-free DNA (dd-cfDNA). The AlloSure test is
intended to assess the probability of allograft rejection in kidney transplant recipients
with clinical suspicion of rejection and to inform clinical decision-making regarding the
necessity of renal biopsy in such patients at least 2 weeks post-transplant in conjunction
with standard clinical assessment.
Amendment 1 (A1): Is an observational study to develop and validate the clinical use of
KidneyCare®.


Phase

N/A


Funding Agency/Sponsor

Industry


Disease

Other


Enrollment Eligibility

KOAR Inclusion Criteria:
1. Patient's health care provider adopts and intends to apply the center's AlloSure
Routine Testing Schedule as part of the information used to manage the patient.
2. Subjects willing to provide written informed consent to participate.
KOAR Exclusion Criteria:
___________________________________________________________
Exclusions for AlloSure® Intended Use
Specimens from patients for whom any of the following are true will not be tested:
1. Recipients of transplanted organs other than kidney
2. Recipients of a transplant from a monozygotic (identical)
3. Recipients of a bone marrow transplant
4. Recipients who are pregnant
5. Recipients who are under the age of 18
6. Recipient who are less than 14 days post-transplant

Accepts Healthy Volunteers

Call +1 (305) 3555418


Contact Information

Study Contact Lissett Moni
Phone Number +1 (305) 3555418
Email ltueros@miami.edu
Get detailed information on ClinicalTrials.Gov

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