Fulvia Verde, Ph.D.
- Associate Professor
- Molecular and Cellular Pharmacology
Dr. Verde's long-term goal is to understand the cellular functions that govern cell shape, and in particular the signaling networks that coordinate cell polarity with cell growth. Alteration of cell polarity and disruption of tissue architecture are a common histological features in cancer. The conserved NDR kinase plays a key role in the control of cell morphology and cell proliferation in several organisms ranging from yeast to mammals. Her laboratory has defined the role of NDR kinase in the spatial control of Cdc42 GTPase, a key regulator of cell polarity, and in promoting polarized cell growth, by inhibiting degradation of specific messenger RNAs.