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About Sylvester

Celebrating 50 years of cancer care and innovation

Sylvester Comprehensive Cancer Center, part of the University of Miami Health System and the University of Miami Miller School of Medicine, is South Florida's academic-based cancer center. It is home to an expert team of more than 3,160+ physicians, researchers and staff working together to discover, develop and deliver world-class care for your specific cancer.

Sylvester strives to reduce the human burden from cancer, that is why its experts offer a wide range of information and programs to help its community make lifestyle choices that reduce risks and promote well-being.

Sylvester is South Florida's only:

  • NCI-designated cancer center
  • Academic-based comprehensive cancer center
  • High Performing cancer center, as recognized by the U.S. News and World Report. It is also rated as high performing in leukemia, lymphoma and myeloma conditions, as well as in surgery for colon, gynecological, lung and prostate cancers.
  • Phase 1 clinical trials program

In addition, it is one of only five Cancer Centers of Excellence in the state of Florida.

Sylvester is currently conducting more than 430 cancer-focused clinical trials.

The gold standard of cancer care

In 2019, Sylvester earned the coveted National Cancer Institute (NCI) designation, becoming the only cancer center in South Florida and one of the 72 with the distinction nationwide, placing us in the top 4% of all cancer centers. In 2024, the NCI reaffirmed Sylvester’s designation. NCI recognizes cancer centers that meet rigorous standards for transdisciplinary, state-of-the-art research focused on developing new and better approaches to preventing, diagnosing, and treating cancer. NCI designation further expands Sylvester’s ability to care for patients and community at large, from increased access to novel therapies and clinical trials, to expanded cancer prevention initiatives, survivorship programs, among others. Learn more about NCI designation.

Highly specialized teams

Sylvester’s experts are world-renowned for advancements in cancer research and care. They work in integrated, collaborative teams to offer you a range of treatment options that lead to better outcomes and higher survival rates. Often sub-specializing in a specific cancer type, the cancer center’s experts are singularly focused on you and your unique treatment.

Most advanced therapies

As South Florida’s only NCI-designated cancer center, Sylvester offers access to the most advanced clinical trials and cutting-edge interventions. In addition to innovative solutions created by experts in Sylvester’s labs, the center can offer options provided through NCI’s Cancer Therapy Evaluation Program and National Clinical Trials Network program. That means you and your loved ones now have greater access to the newest, most advanced cancer therapies available, right here, at home.

Unique treatment plans

Just as every patient is different, so is every cancer. Sylvester’s highly dedicated teams are solely focused on achieving the best possible outcomes by crafting tailored treatment plans that address your genetic profile and the individual characteristics of your cancer. This includes using leading-edge technology such as MRI-guided therapy systems, robotic high-intensity focused ultrasound devices, Gamma Knife radiosurgery, and much more.

Phase 1 Clinical Trials Program

Sylvester has the only South Florida phase 1 clinical trials program — the first step in evaluating how patients respond to novel investigational treatments. Since 2012, Sylvester has tripled the number of interventional treatments it offers, and now provides therapies that can’t be found at any other cancer center in the world.

The goal of phase 1 clinical trials is to determine the safety and efficacy of new treatments in patients with cancer. They may help develop more treatment options and, most importantly, give hope for cancer patients.

Learn more about Sylvester’s phase 1 clinical trials program.

With you every step of the way

Sylvester designs every facet of the patient journey with you and your family in mind — from a comfortable setting and convenient amenities to support services such as massage therapy, nutritional counseling, and individual and family therapy.

Once you’ve completed treatment, Sylvester offers Survivorship Programs that include support groups, seminars, workshops and other resources for your long-term care. Designed through research, the programs also address the social, economic and physical effects cancer has among patients after treatment.

Learn more about survivorship programs.

Multiple convenient locations across South Florida

Sylvester's experts are available in locations across South Florida, from north Broward to south Miami-Dade.

Visit one of Sylvester’s convenient locations.