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Dr. Portelance clinical research concentrates on the development of innovative ways to improve outcomes from radiation treatment for gastrointestinal and gynecological cancer. It includes using magnetic resonance image-guided adaptive radiation therapy (MRI-g ART) to precisely target tumors of the abdomen and pelvis. Her research program also explores better ways to integrate brachytherapy in the management of liver (dosimetric studies to understand for intraarterial Yttrium-90 treatment) and gynecological cancer (MRI-g endocavitary and interstitial brachytherapy.