Dr. Schaefer Solle's research interests focus on occupational cancer risks and improving cancer screening in underserved communities. She has played a critical role in the conception of the Firefighter Cancer Initiative (FCI), a multi-faceted project funded by the state of Florida to study firefighters' exposure to carcinogens, examine their cancer risk, and develop methods of education about prevention and early detection. She has led multiple projects within FCI focusing on the epidemiology and cancer screening behaviors of active and retired firefighters.