Neuroendocrine tumors can originate from many places in the body, however pancreatic NET is among the top three site of origin. UM-Sylvester NET program is the only dedicated clinical and research program focused on NETs in South Florida. All NET cases are discussed at our weekly multi-disciplinary NET tumor board. Our patients have access to cutting edge clinical trials including novel combination PRRT (Peptide receptor radionuclide therapy) studies and immunotherapies studies.
These tumors form in hormone-creating cells, or islet cells, of the pancreas. Tumors that form in islet cells are called islet cell tumors, pancreatic endocrine tumors, or pancreatic neuroendocrine tumors, also called pancreatic NETs or PNETs. When pancreatic NETs are malignant, they are called pancreatic endocrine cancer or islet cell carcinoma.
Most pancreatic NETs are functional tumors.
- Functional tumors make extra quantities of hormones, such as gastrin, insulin, and glucagon, that cause signs and symptoms.
- Nonfunctional tumors do not make extra hormones. Signs and symptoms are precipitated by the tumor as it spreads and grows. Most nonfunctional tumors are malignant, or cancerous.
Types of functional pancreatic NETs
This is a tumor that grows in cells that make gastrin. Gastrin is a hormone that helps digest food by causing the stomach to release an acid.
This tumor forms in cells that produce insulin. Insulin controls the amount of glucose or sugar in the blood. It moves glucose into the cells to produce energy.
This tumor forms in cells that manufacture glucagon. Glucagon is a hormone that boosts the amount of glucose in your blood. It causes the liver to break down glycogen.
VIPoma is a pancreatic neuroendocrine tumor which secretes vasoactive intestinal peptide. It may also be called Verner-Morrison syndrome.
Found in cells that make somatostatin, these are rare neuroendocrine tumors that arise in the pancreas.
Why Choose Sylvester Comprehensive Cancer Center?
Sylvester is an NCI-designated cancer center. The National Cancer Institute has recognized Sylvester for its outstanding work conducting research in its laboratories, treating patients in its clinics and hospitals, and reaching out to medically underserved communities with innovative prevention strategies.
Specialized care that improves outcomes. At our center, patients experience survival rates up to 14 percent higher than the national average for early- and late-stage pancreatic cancer. Our multi-disciplinary team of pancreas cancer experts offer innovative treatment approaches, high-tech and modern minimally invasive surgical approaches, ground-breaking clinical trials, and cutting-edge radiation technologies. We are committed to a thorough workup of your cancer to provide an individualized treatment strategy for your unique tumor so you may experience the best potential outcomes and the fewest possible side effects.
One of few Pancreatic Cancer Research Institutes in the United States. You have increased access to leading-edge treatments and additional resources for patients and families.
More cancer clinical trials than any other South Florida hospital. If appropriate for your cancer and stage, our clinical trials provide you with easy access the very newest ways to treat and potentially cure your cancer.
Multidisciplinary care teams. Your care team is made up of experts in all aspects of your exact type of cancer. All of your physicians, nurses and more collaborate to save lives.
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