Contact Us
Investigator / Contact Person
Xiangxi Xu, Ph.D.
Lab
305-243-1433
Office
305-243-1750
Email
xxu2@med.miami.edu
Research
The lab is interested in ovarian cancer biology and therapies, embryonic stem cells, and early embryogenesis. Currently several key projects are planned in the lab:
- We study the roles of AMH (Anti-Mullerian Hormone) in regulation of progenitor cells in ovarian cancer development, pathology in menopause, and the influences on sex-biased biology.
- We investigate the mechanisms of Taxol in stabilizing microtubules and killing of cancer cells, and mechanisms and strategies to overcome drug resistance.
- Based on a recent lab finding, we are developing application of low intensity ultrasound to impact microtubules as a strategy in countering side efforts in cancer chemotherapy, namely myelosuppression, peripheral neuropathy, and alopecia.