Nipun B. Merchant, M.D.
- Professor
- Associate Director of Translational Research
- Chief Surgical Officer
- Vice Chair of Surgical Oncology Services
- Director of Surgical Oncology Research
Department:
- Surgery
Research Interest
Dr. Merchant investigates how alterations in RAS and STAT3 signaling pathways affect the tumor stroma and immune microenvironment in pancreatic cancer. Using genetically engineered mouse models and 3-dimensional in vitro models, Dr. Merchant's lab studies how cross-talk between these pathways in the tumor and stroma affect epithelial-to-mesenchymal transition, changes in the tumor microenvironment and alterations in immune response to enhance therapeutic efficacy in pancreatic cancer.