Alexander Zaika, Ph.D.
- Associate Professor
Dr. Zaika’s research is devoted to the understanding of human tumorigenesis. His search for answers led him to upper gastrointestinal tumors, gastric and esophageal adenocarcinomas. One of the most important reasons why Dr. Zaika decided to focus his research on these tumors is their unique etiologies. The strongest known risk factor for gastric cancer is a microbial agent, Helicobacter pylori. Etiological factors for esophageal adenocarcinoma are different but no less interesting. The strongest risk factor for esophageal adenocarcinoma is gastroesophageal reflux disease. In the center of tumorigenic alterations induced by GERD is persistent cycles of damage-regeneration of esophageal tissues induced by gastroesophageal reflux. Thus, Dr. Zaika is interested in how H. pylori and GERD induce tumors.