Luisa Cimmino, Ph.D.
- Assistant Professor
- Biochemistry & Molecular Biology
Dr. Cimmino’s current research interests are to understand how environmental factors, such as micronutrients, influence the activity of epigenetic regulators to drive hematopoietic stem cell development, differentiation, and transformation. The TET proteins, enzymes that regulate DNA methylation in the genome, play an important epigenetic role in the regulation of normal and malignant hematopoiesis. Using deletion and reversible RNAi transgenic mouse models she has shown that these enzymes have lineage-specific and non-redundant roles as tumors suppressors.