Dr. Pawha conducts aging research including human aging research concerning inflammation, immune dysfunction, vaccine responses, and HIV and aging, as well as monkey model aging studies to explore the microbiome, immunity, vaccine responses, lymph node architecture, co-morbidities, immunotherapy approaches to augment vaccine responses, and SIV infection. She also studies Infant immune responses in HIV exposed uninfected and infected infants and aims to find strategies to cure HIV in infants. Additionally, she investigates T follicular helper cells and interaction with B cells for antibody responses and conducts collaborative projects in immunology, colon polyps, kidney transplants, and HPV.