Research Focus

Research Focus of the lab is to:

1. Comprehensively characterize long-lasting adverse effects of chemotherapy on the function of hematopoietic and immune systems and their responses to viral and bacterial infections.
2. Investigate the role of inflammation and genetic and epigenetic changes in chemotherapy-induced long-term functional impairments of the hematopoietic and immune systems.
3. Test whether - a) combined treatment with chemotherapy and different non-steroidal anti-inflammatory drugs, and b) novel targeted delivery of chemotherapy drugs into the primary tumors and metastatic sites, represent new clinically applicable treatment approaches which can minimize or prevent long-lasting adverse effects of therapy by significantly 1) decreasing systemic inflammation and/or 2) off-target accumulation of chemotherapy drugs.