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Lossos Lab

Pathogenesis and treatment of Lymphomas

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Investigator / Contact Person Izidore Lossos, M.D.

Research Focus

The laboratory is investigating pathogenesis of different subtype of non Hodgkin's lymphomas as well as novel therapeutic approaches. Specific interests are in: 1) Function of the HGAL gene in lymphoma dissemination and BCR signaling; 2) Role of LMO2 protein in pathogenesis of DLBCL; 3) Alterations in DNA repair mechanisms in lymphoma; 4) pathogenesis of orbital marginal zone lymphomas; 5) Function and targeting of PRMT5 protein in DLBCL .