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Merchant Lab

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Investigator / Contact Person Nipun B. Merchant, M.D.

Research Focus

My lab investigates how alterations in RAS and STAT3  signaling pathways affect the tumor stroma and immune microenvironment in pancreatic cancer. Using genetically engineered mouse models and 3-dimensional in vitro models, we study how cross-talk between these pathways in the tumor and stroma affect epithelial-to-mesenchymal transition, changes in the tumor microenvironment and alterations in immune response to enhance therapeutic efficacy in pancreatic cancer. 

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