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Pahwa Lab

Immunology Lab, Immunity in Aging and infections

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Investigator / Contact Person Savita Pahwa

Research Focus

The Pillai group was first to discover innate-adaptive networks inducing histocompatibility-mismatched stem cell transplant (SCT) tolerance, defining the role of invariant natural killer T cells (iNKT cells) in setting up myeloid and Foxp3+Tregulatory cell activity and regulating GVHD while maintaining graft-versus-tumor activity (GVT). This has successfully translated to novel SCT techniques for children and adults nationally. The group is developing novel haplo-SCT strategies and iNKT immunotherapies for cancer, infectious diseases, and autoimmunity.