Research Focus

Our lab is interested in understanding mechanisms of resistance to therapy in cancer, with a particular focus on the non-Hodgkin lymphomas. Diseases in this diverse group of more than 50 cancer diagnoses derive from B and T lymphocytes, which regulate and help carry out immune function. While many lymphomas may be curable or manageable through a series of treatments over a period of years, more than 25,000 Americans die annually from these diseases. By understanding the pathways within lymphoma cells that drive them to become resistant to treatment, we lay the groundwork for novel treatment approaches suitable for evaluation in clinical trials.