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Contact Information

Papanicolau Cancer Research Bldg 519 (R136)
Noula D. Shembade, Ph.D.

Noula D. Shembade, Ph.D.

  • Associate Professor
Department:
  • Microbiology and Immunology
Research InterestPage 1
Chronic inflammation mediated by a transcription factor, NF- κB, in HTLV-1, EBV, and KSHV-infected cells plays a critical role in the development of oncogenic virus-associated malignancies. One of the main mechanisms of persistent NF- κB activation in oncogenic virus-infected cells is dysregulation of the function of host factors by viral oncogenes. However, the cellular host factors required for persistent NF- κB activation in oncogenic virus-infected cells remains largely unknown. Thus, their focus determines the host factors that are involved in chronic activation of NF- κB and inflammation in HTLV-1, EBV, and KSHV-infected cells.