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Cooke Lab

Molecular and Translational Cancer Research

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Investigator / Contact Person Mariana Cooke, M.D., Ph.D., MTR

Research Focus

Understanding the intricacies of deregulated signaling networks as the pathophysiological basis underlying tumorigenesis, cancer progression and metastatic dissemination is at the core of my research interests. These studies emphasize the role of Rho small GTPases and oncogenic kinases in clinically relevant models with translational applicability of epithelial-derived solid tumors. My research projects overarch key disarranged nodal signaling pathways leading to molecular aberrancies.

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