Skip to Main Content

Anatomy of Impact

Diagram of after an endocardiogram procedure
a.

Glioblastoma Neuro-Oncology
Our researchers are more accurately targeting glioblastoma therapies by pairing machine learning with MRI-guided radiation therapy.

b.

Skin Cancer
Tony Beyer’s successful melanoma treatment at Sylvester led him to fund the Beyer Family Skin Cancer Prevention Initiative.

c.

Lung Thoracic Cancers
Sylvester’s new scoring system links social determinants of health and survival outcomes in lung cancer patients undergoing surgery and treatment.

d.

Breast
The FastER clinical trial will examine if exercise and fasting restore circadian rhythms and enhance treatment tolerance in advanced breast cancer survivors.

e.

Pancreatic-Gastrointestinal
A combination of targeted therapies with immunotherapy was found to address one of the significant reasons pancreatic cancer is so notoriously treatment-resistant.

f.

Lymphoma
Our researchers showed whole genome sequencing detects DNA structural variations and provides more precise data to track mutations associated with Hodgkin lymphoma.

g.

Endometrial–Gynecological
U.S. Black women have higher endometrial cancer rates than French Caribbean women. Sylvester researchers found that diet and health care access, not just ancestry, affect these rates.

h.

Transplant and Cellular Therapy
28 open studies with stem cell transplant patients.

i.

Sarcoma
Joel Horowitz’s donation established the Horowitz Solitary Fibrous Tumor Initiative thanks to the outstanding care received from Sylvester.

j.

Glioblastoma-Neuro-Oncology
Our scientists pioneered a machine-learning algorithm that can combine large datasets from multiple sources to pinpoint cancer-driving enzymes and potentially target them for treatment.

k.

Pediatric
A $3.5 million commitment will establish the Dwoskin Children’s Cancer Research Fund to support transformative research on brain tumor therapies.

l.

Head and Neck
Our researchers introduced an inexpensive and non-invasive oral rinse screening that could be essential in the early detection of mouth and throat cancers.

m.

Mesothelioma (Lung)-Thoracic Cancers
Sylvester researchers demonstrated how reducing health disparities in patients with mesothelioma can improve their overall survival by 30% when treated early.

n.

Pancreatic-Gastrointestinal
Published research identified immature neutrophils as the main culprit pancreatic tumors use to promote immunosuppression and treatment resistance.

o.

Multiple Myeloma
Our Sylvester Myeloma Research Institute revealed the risks of multiple myeloma treatments, shedding light on potential future malignancies from aggressive blood cancer therapies.

p.

Stomach-Gastrointestinal
Country of birth, not just geographic region, is a crucial risk factor for gastric intestinal metaplasia, a precursor of stomach cancer.

q.

NET Tumors
Dr. Aman Chauhan’s addition to Sylvester as its Neuroendocrine Tumor Program leader shows the cancer center’s commitment to its depth of research expertise.

r.

Leukemia
The Appelbaum Foundation, Inc., awarded our researchers a total of $600,000, divided over two years, to research graft-versus-host disease in leukemia patients, post allogenic transplants.

s.

Liver Cancer
In a collaborative study, Sylvester researchers helped identify racial and ethnic differences and emerging trends for this highly fatal disease. The review was published in the journal Clinical Gastroenterology and Hepatology.

t.

Prostate–Genitourinary
Despite Black men having a higher risk of developing prostate cancer, Sylvester researchers discovered they are less likely to get early comprehensive genetic profiling of their tumors compared to Caucasian males.