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Biospecimen Services

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Biospecimen Services

The BSSR collects tumors, non-neoplastic tissue, peripheral blood, CSF and cystic fluid samples.  This includes neoplastic and non-neoplastic samples from multiple organs such as lung, kidney, liver, breast, pancreas, thyroid, thymus, lymph nodes, gastro-intestinal track, and soft tissue.

2 Microscopes for slide review

Services Include

Participant screening and enrollment under the BSSR IRB consent within:

  • University of Miami Hospital
  • Sylvester Comprehensive Cancer Center
  • Jackson Memorial Hospital
  • Bascom Palmer Eye Institute

Biospecimen Procurement (tissue, blood, fluid)

  • Fresh (upon request), Flash-frozen, Frozen in OCT (upon request), Formalin-fixed

Storage for all BSSR procured samples (when needed) within the Biorepository at Hussman Institute for Human Genomics (HIHG)

Storage temperatures:

  • Double-door refrigerators (4°C)
  • Freezers (-20°C)
  • Ultra-low Freezers (-80°C)
  • Liquid nitrogen (-196°C)

Biological Sample Processing

  • Plasma/Buffy coat
  • Extraction of genomic DNA and RNA isolation (by the Biorepository at HIHG upon request)
  • Patient-Derived Xenografts (PDX) (by Daniel Bilbao PhD, Developing Cancer Modeling Shared Resource at SCCC)
  • Digital whole slide scanning including H&E stain
  • Detailed microscopic image of collected tissue (upon request at no additional charge)
  • Tumor viability assessment and necrosis percentage (upon request at no additional charge)

Biobanking

  • Participant screening and enrollment under the BSSR IRB consent within:
    • University of Miami Hospital
    • Sylvester Comprehensive Cancer Center
    • Jackson Memorial Hospital
    • Bascom Palmer Eye Institute
  • Biospecimen Procurement (tissue, blood, fluid)
    • Fresh (upon request), Flash-frozen, Frozen in OCT (upon request), Formalin-fixed
  • Storage for all BSSR procured samples (when needed) within the Biorepository at Hussman Institute for Human Genomics (HIHG). Storage temperatures:
    • Double-door refrigerators (4°C)
    • Freezers (-20°C)
    • Ultra-low Freezers (-80°C)
    • Liquid nitrogen (-196°C)
  • Biological Sample Processing:
    • Plasma/Buffy coat
    • Extraction of genomic DNA and RNA isolation (by the Biorepository at HIHG upon request)
    • Patient-Derived Xenografts (PDX) (by Daniel Bilbao PhD, Developing Cancer Modeling Shared Resource at SCCC)
    • Digital whole slide scanning including H&E stain
    • Detailed microscopic image of collected tissue (upon request at no additional charge)
    • Tumor viability assessment and necrosis percentage (upon request at no additional charge)

Non-Therapeutic Trial Support

  • Study Management
    • Study start-up services
    • Regulatory support
    • IRB support, internal & external
    • Continuing reviews
    • Sponsor/CRO communications
    • Document preparation
    • Database implementation and management
  • Study Coordination
    • Screening and recruitment of subjects
    • Consenting/enrollment and follow-up
  • Biospecimen Collection
    • Blood, tissue and biofluid collection
    • Biospecimen processing
    • Specimen distribution and shipment
  • Data Management
    • Electronic data capture
    • Subject follow up
    • Sample tracking