Cancer Modeling Shared Resource

Cancer Modeling (CMSR) is a newly developing resource at Sylvester. The goal of the CMSR is to provide mouse models of cancer to allow investigation of novel anti-cancer treatments in a pre-clinical setting, including cell line, xenograft, and patient derived (PDX) models of cancer.

The CMSR will also provide uniform care and provision of novel therapies under standard operating procedures. Lastly, it will provide assessment of anti-cancer activity in a very controlled, reproducible setting.

The CMSR will mirror every aspect of human cancer diagnostics, treatment and care, and provide qualified, cost effective and state-of-the-art services to foster cancer research advancements, and accelerate the discovery of tailored anti-tumor therapies leading to patient benefit. It will consist of an integrated shared resource composed of four components to support four key activities:

Modeling human disease
Devising treatment protocols
Using noninvasive imaging for diagnosis and evaluation of responses to treatment
Perform pathological analysis of targeted cancer therapies